κοπιάω

κοπιῶ (3 person plural κοπιουσιν (for κοπιῶσιν), Mt 6:28 Tr; cf. ἐρωτάω, at the beginning); 1 aorist ἐκοπίασα; perfect κεκοπίακα (2 person singular κεκοπίακες, Rev 2:3 L T Tr WH, cf. (Winers Grammar, § 13, 2 c.); Buttmann, 43 (38) (and his translation of Apollonius Dyscolus, p. 54 n.; Tdf. Proleg., p. 123; WHs Appendix, p. 166; Sophocles' Lexicon, p. 39)); (κόπος, which see);
1. as in Aristophanes, Josephus, Plutarch, others, to grow weary, tired, exhausted, (with toil or burdens or grief): Mt 11:28; Rev 2:3; κεκοπιακώς ἐκ τῆς ὁδοιπορίας, Jn 4:6 (ὑπό τῆς ὁδοιπορίας,Josephus, Antiquities 2, 15, 3; δραμοῦνται καί οὐ κοπιασουσι, Isa 40:31).
2. in Biblical Greek alone, to labor with wearisome effort, to toil (the Sept. for יָגַע ); of bodily labor: absolutely, Mt 6:28; Lk 5:5; Lk 12:27 (not Tdf.); Jn 4:38; Acts 20:35; 1 Cor 4:12; Eph 4:28; 2 Tim 2:6 (cf. Winers Grammar, 556 (517); Buttmann, 390 (334)); τί, upon a thing, Jn 4:38. of the toilsome efforts of teachers in proclaiming and promoting the kingdom of God and Christ: 1 Cor 15:10; 1 Cor 16:16 (cf. Jn 4:38); followed by ἐν with the dative of the thing in which one labors, ἐν λόγῳ καί διδασκαλία, 1 Tim 5:17; ἐν ὑμῖν,among you, 1 Thess 5:12; ἐν κυρίῳ (see ἐν, I. 6 b., p. 211b middle (L brackets the clause)), Rom 16:12; εἰς τινα, for one, for his benefit, Rom 16:6; Gal 4:11 (cf. Buttmann, 242 (200); Winer's Grammar, 503 (469)); εἰς τοῦτο, looking to this (viz. that piety has the promise of life), 1 Tim 4:10; εἰς ὁ, to which end, Col 1:29; εἰς κενόν, in vain, Phm 2:16 (κενῶς ἐκοπίασα, of the frustrated labor of the prophets, Isa 49:4).